(STILL) DESIGNED TO HELP KEEP RUNNERS RUNNING. The Nike React Infinity Run Flyknit 2 continues to help keep you running. A refreshed upper uses Flywire technology that combines with Flyknit for support and breathability where you need it. The high foam heights provide soft responsiveness and long-lasting comfort. It's still one of our most tested shoes, designed to help you feel the potential when your foot hits the pavement.